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Scientists deemed the dye an acute toxin.
Similarly, the development of Arafat's final symptoms, and his death from a blood condition known as disseminated intravascular coagulation, or DIC, was "compatible with an acute toxin pathology, possibly the radiosotope polonium-210".
Not only is it toxic to workers-the Environmental Protection Agency classifies it as a Category I acute toxin, the most deadly kind-it also is 50 times more destructive to the ozone layer than chlorine atoms from chlorofluorocarbons. Radiation could offer a reasonable alternative.
Our understanding of the health risks of HAB toxins, and therefore our ability to mitigate those risks, is incomplete until we know the human health effects associated with both chronic and acute toxin exposures.
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The report's authors said: "As long as acute toxins remain the basis of agricultural pest control practices, society will be forced to weigh the benefits of pesticides against their collateral damage.
As Lustig points out, sugar and high-fructose corn syrup are certainly not "acute toxins" of the kind the F.D.A. typically regulates and the effects of which can be studied over the course of days or months.
Acute toxins delivered via ground-based operations did an acceptable job of getting rid of rodents, but the delivery was inefficient and the poisons led to an inhumane end for those creatures.
To examine the applicability of these findings in vivo, acute toxin-induced retinal cell death was initiated by intravitreal injection of SSP.
Using a mouse model of acute toxin-induced liver injury, they identify an interaction between the extracellular matrix and hepatocytes that promotes cell survival.
Because we administered non-native endostatin in this trial, we cannot rule out that the endostatin domain still intact with the rest of the type XVIII collagen could elicit the protective effects during acute toxin-induced liver injury.
For acute lethal toxin challenge in vivo, mice were injected intraperitoneally with anthrax lethal toxin (2 µg/g body weight, LF+PA at 1∶2 ratio) and were sacrificed under anesthesia (ketamine/xylazine: 3∶1, 1.32 mg/kg, i.p.,) at 2, 4 and 18 hrs after lethal toxin injection.
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