Indeed, the same degree of arterial hypertension may be associated with symptoms of acute target-organ damage in one individual or be completely asymptomatic in another.
This problem may be especially acute for target beneficiaries whose premium payments are fully paid out of public subsidies.
The results demonstrate that HIV-specific CD4+ T cell responses at the time of acute infection target various proteins and that the overall responses declined over time.
Acute infections target mucosal cell surfaces (lung, genital tract or eye).
In addition, given pH is a physiological parameter that can be manipulated, pH-weighted imaging has the potential to meet the criteria of a treatment-relevant acute imaging target (Wintermark et al., 2013).
The overall major adverse coronary and cerebral events (22.6% versus 20.1% in men and women, respectively, P=0.984), including cardiac death, non-fatal acute MI, target vessel revascularization and cerebral vascular events, showed no significant difference.
It was proposed that in vertebrates, low stress p53 targets promote ROS detoxification, DNA repair while acute stress targets induce apoptosis or senescence [ 1].
The prostate is considered to be a non-essential organ and therefore immunological treatments utilising prostate TAAs will not cause acute off-target toxicity [9, 18].
However, recent observational data suggest that in patients with pre-existing poorly controlled type 2 diabetes (defined as an HbA1c ≥7%) prior to their acute illness, targeting glucose concentrations < 10mmol/l is associated with harm [1].
