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Oestrogens have acutely improved islet survival following transplantation, as demonstrated by E2-mediated acute suppression of graft apoptotic beta cells.
However, activation of the known 5-HT autoreceptors does not appear to be required for acute suppression of 5-HT synthesis by citalopram [54].
This result suggests that acute suppression of mTOR via AMPK activation during the short induction phase of LTP prevents expression of chronic L-LTP.
In the mammalian retina, the light sensitive RGCs that express the photopigment melanopsin [15] [18] comprise a specific subset (<1%) of large sized ganglion cells that regulate the photic synchronisation of circadian rhythms and more generally, a spectrum of "non-visual responses" to light including the acute suppression of melatonin, pupillary constriction, alertness and masking [19] [23].
Heroin use results in acute suppression of luteinizing hormone (LH) release from the pituitary followed by a secondary drop in plasma testosterone levels (Mirin et al 1980).
In the present study, we tested the hypothesis that acute suppression of lipolysis would improve the rate of glucose metabolism specifically by increasing muscle glycogen synthesis.
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A 2nd concern in the intensive care unit is acute adrenal suppression secondary to bolus etomidate therapy because it may be deleterious in patients with septic shock.
A 3 hr light pulse from ZT 14 17 was used to measure acute activity suppression (masking) by light.
The hematopoietic progenitor cells (HPCs) and a small amount of hematopoietic stem cells (HSCs) undergo apoptosis after exposure to IR, thus resulting in acute BM suppression within days [ 3].
Although it is not known whether the CS for circadian entrainment and phase shifting is the same as the CS for acute melatonin suppression, the literature suggests that these responses to light are similar.
To more rigorously measure masking, we first examined acute activity suppression of wheel-running activity by a 3 hr light pulse from zeitgeber time (ZT) 14 17 and found no significant difference in masking in Lhx1lox/lox and Six3-Cre Lhx1lox/lox mice.
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