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The first version of the PELOD score [7] has been used over the last few years as an outcome measure in studies in specific subpopulations, such as sepsis [13], hematopoietic stem cell transplant [14], acute respiratory dysfunction syndrome [15], extracorporeal life support [16], drowning [17], or seizure [18].
ARDS = acute respiratory dysfunction syndrome; CPR = cardiopulmonary resuscitation; CT = computed tomography; ICU = intensive care unit.
The inclusion criterion was the initiation of mechanical ventilation for acute respiratory dysfunction characterised by a PaO2/FiO2 ratio < 300 mmHg, where the acute respiratory dysfunction was primarily due to a direct or indirect inflammatory insult to the lung.
The girl was treated with mild hypothermia for 72 hours and developed acute respiratory dysfunction syndrome and sepsis.
The girl was treated with mild hypothermia and developed acute respiratory dysfunction syndrome and sepsis, but recovered without neurological deficits.
However, neither the ideal ventilation strategy for patients with massive brain damage nor the underlying biological mechanisms leading to acute respiratory dysfunction are clearly defined.
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The occurrence of organ dysfunction, including acute respiratory distress syndrome, renal dysfunction, metabolic acidosis, and hematologic dysfunction, based on biomarker levels is shown in Figure 5.
Development of novel prognostic, diagnostic, and treatment options will provide major benefits for millions of patients with acute or chronic respiratory dysfunction, cardiac-related disorders, esophageal problems, or other diseases in the thorax.
Some patients also develop acute respiratory or cardiac dysfunction, manifested as hypertension, tachycardia, angina pectoris, or dyspnea.
Our results are consistent with the hypothesis that deficits in BDNF-TrkB signaling contribute to breathing abnormalities in RTT and support the possibility that BDNF loop-domain mimetics could be useful in the acute treatment of respiratory dysfunction, including dysregulated responses to behavioral arousal, in RTT patients.
Patients were divided into those with hepatic dysfunction, acute respiratory distress syndrome (ARDS), acute renal dysfunction, and cardiovascular failure (CV) by standard definitions [ 14].
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