Sentence examples for acute mode from inspiring English sources

However, the acute mode of onset and the need for similar doses of insulin at onset in interferon-associated type 1 diabetes compared with type 1A diabetes may be partly related to insulin resistance caused by interferon α (8).

To assess the potential hazards of Bt Cry insect-control proteins that have an acute mode of action, the US Environmental Protection Agency US EPAA, 2000 ) requires the use of high (hazard) acute doses (∼gram/kg body weight [BW]) where feasible.

But the economy began to slow down in 1979 and was in acute crisis mode by 1980, having lost about 1.5 million jobs from its previous peak.

Investigating further the temporal response of acute-stochastic and collective modes we observed auto- and cross-correlation profiles of acute-stochastic mode is similar to immune-related genes whereas the average response of randomly selected 80 ORFs in collective mode is scaled to genome-wide response (Figure 4G H, and Figure 3A), thus demonstrating that collective mode is scalable.

Unlike acute-stochastic mode, collective mode possesses average points in plot which follows flat profiles.

Furthermore, unknown processes (U) are not indicated for acute-stochastic mode.

were upregulated in WTc+, which indicates immune-related genes are not restricted to the acute-stochastic mode alone (Table 2).

Acute-stochastic mode is largely immune-related response, while collective mode participates in diverse regulatory processes normally unrelated to immunity that transform the initial local response to the antigenic stimulus into a general state change of the cell.

Using DAVID analysis platform [28], the majority of biological processes of acute-stochastic mode is related to immune system, defense response, inflammatory response, etc., specifically activated by M and T (Table 1, p<0.05).

Wildtype upregulated ORFs in acute-stochastic mode (WTa+), are constituted of a single group of 80 ORFs whose average expression change in wildtype (M+T+MT+U) is 1.22, MyD88 KO (T+U) is 0.46, TRIF KO (M+U) is 0.80 and DKO (U) is 0. Hence, the relative contribution of each signaling to the activation of acute-stochastic mode ORFs is determined: M = 0.80, T = 0.46, MT = −0.04, U = 0.

Further correlation analyses reveal genome-wide response is biphasic, i) acute-stochastic mode consisting of small number of sharply induced immune-related genes and ii) collective mode consisting of majority of weakly induced genes of diverse cellular processes which collectively adjust their expression level.