The phrase "acute lethal effects" is correct and usable in written English.
It can be used in contexts related to toxicology, environmental science, or health to describe immediate and severe harmful impacts of a substance or condition.
Example: "The study revealed that the chemical had acute lethal effects on aquatic life, leading to significant population declines."
Alternatives: "immediate fatal effects" or "severe lethal impacts."
We explored the relationship between land use around the 10 investigated ponds, population genetic diversity as measured by neutral genetic markers (polymorphic allozymes) and the tolerance of the populations originating from these ponds to acute lethal effects of two model toxicants, the pesticide carbaryl and the metal potassium dichromate.
Because the chronic and subchronic effects in aquatic organisms might be more relevant than the acute lethal effects, studies addressing the exposure of biota in cyanobacteria-rich lakes have attracted substantial attention (Ibelings and Chorus 2007; Ibelings and Havens 2008).
Due to the acute lethal effects measured on larval Aedes aegypti, and the urgent need for new insecticidal molecules, considerable efforts were made to isolate and identify the compounds responsible for the leaf litter toxicity [22] [25].
Treatment with diethyldithiocarbamate and thiram also protected mice from the acute lethal effects of VDC.
The fact that short-term activation of RAS sensitizes cells to these chemotherapeutic drugs, such as camptothecin, topotecan, doxorubicin and daunorubicin, suggests that this represents an acute synthetic lethal effect, likely due to direct conflict of the cells' response to drug-induced DNA damage with the activated signaling pathways driven by RAS.
Mice were more sensitive than rats both to the acute lethal and hepatotoxic effects of VDC.
Disulfiram treatment reduced the acute lethal and hepatotoxic effects of inhaled VDC and reduced the levels of covalent bound radioactivity in the liver and kidney after the intraperitoneal administration of 14C-VDC.
To study the effects of calcium regulation on acute lethal anoxic injury and the effects of inhibition of respiration with cyanide, three experimental systems were utilized: Ehrlich ascites tumor cells, isolated rabbit proximal tubule segments and suspended or cultured rat proximal tubule cells.
It has been shown that melatonin, at a dose as high as 250 mg/kg, is nontoxic and that high doses of melatonin are effective in protecting mice from lethal effects of acute whole-body irradiation [ 10].
In PHD-1-deficient myofibres, oxygen consumption was reduced, leading to protection of the cells against the lethal effects of acute severe hypoxia [ 25].
Although these populations differ significantly in development of chronic effects of arsenic, acute lethal toxicity requires large amounts more of arsenic in either population.
