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Nevertheless, no direct link between acute fluctuation of glycemia and oxidative stress has been consistently reproduced in human studies [ 36, 37].
In our study, daily acute fluctuation of systemic glucose was a predictor of the development of cerebral metabolic distress after adjusting for the presence of DCI.
In vitro studies [ 34, 35] have shown that acute fluctuation of glycemia induced a greater triggering effect on oxidative stress than did chronic sustained hyperglycemia.
Delirium is an acute fluctuation in mental status that manifests with inattention, disorganized thinking, and/or an altered level of consciousness [ 1].
Specificity and PPV of ONSD for ICP >20 mmHg are substantially decreased in patients demonstrating acute fluctuation of ICP between high and normal.
In our study, point-in-time ONSD measurement was less accurate for the identification of point-in-time ICP elevation (>20 mmHg) when acute fluctuation was present using two different definitions of SAIF.
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He suffered what were described by Channel 5 as acute fluctuations in blood pressure.
This study tested the relationship between metacognitive factors, intolerance of uncertainty, anxiety, and the predictability of, and distress associated with, acute fluctuations in symptoms in idiopathic Parkinson's disease (PD), when controlling for disease parameters.
Previous investigators have studied skin autofluorescence during oral glucose tolerance testing and noted no changes related to acute fluctuations in blood glucose (23).
65 Unlike conditions of chronic oxidative stress, acute fluctuations in ROS and/or transient synthesis of these highly reactive molecules function as inter- and intracellular signaling second messengers.
Patients with SAH may be more vulnerable to glycemic variability if these acute fluctuations trigger cerebral metabolic distress and lead to secondary brain injury.
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