One possible reason why anemia was not observed in our studies is that we conducted an acute exposure design; the other studies where anemia was seen are all repeat dose studies.
Nevertheless, previous studies from our group have shown that same carbamate is capable of inducing significant increases in TBARS and GGT levels when administered orally to male rats at a dosage of 5 mg/kg/day in an acute exposure design [ 9].
The use of "as needed" or "pro re nata" (PRN) range opioid analgesic orders is a common clinical practice in the management of acute pain, designed to provide flexibility in dosing to meet an individual's unique needs.
Whilst multiple studies in this review [41, 63, 64, 76, 77] use acute response designs and receive poor methodological quality rating, they may have some generalizable merit for sports medicine and science readers.
However, those approaches for stroke are limited to acute measures designed to restore perfusion and to protect ischemic cells from death in the acute phase, which are unable to replace damaged or lost neural cells [ 4].
On its website Castlebeck describes Winterbourne View as "a purpose designed acute service, offering assessment and intervention and support for people with learning disabilities, complex needs and challenging behaviour".
Redouté's powers of observation, acute sense of design and brilliant palette elevated him to the realm of most influential botanical artist of his time.
Study Design: Acute studies were conducted on 13 canines implanted with Itrel II systems with or without PCA innervation.
Some are of the creature-comfort variety, like the Dixie Cup, which was designed by Lawrence Luellen, an American, in 1908, but acquired by the Modern only in 2005 — an unusual time lag considering the museum's acute attention to design.
Because chronic obstructive pulmonary disease (COPD) is a chronic progressive disorder characterized by slow onset and acute exacerbations, the design of animal models able to reproduce these characteristics is difficult.
