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Conversely, the Nrf2-knockout mice are prone to acute damages and tumor formation induced by various harmful chemicals (Ramos-Gomez et al., 2001; Wang et al., 2008).
Regardless of our collective actions today, there will be irreplaceable losses and acute damages, which is a result of historical and current-day emissions.
Thus our study offers proof-of-concept evidence that cocktail of clinical compounds improving cell reprogramming favors tissue recovery after acute damages, which is an attractive strategy for regenerative purpose.
Overall, PrP-SIRT1 and WT male littermates exhibited similar responses to MPTP toxicity in terms of acute damages to nigrostriatal DA neurons, and proliferation/remodeling of neighboring astrocytes.
Betaine metabolism occurs predominantly in the liver [ 20], and DEN is able to generate acute damages in the rat liver [ 30].
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In case of acute damage, wound healing processes are very important to protect the inner tissues.
Cerebral ischemia reperfusion is a classic example of reactive oxygen species (ROS) mediated acute damage to brain.
X-ray pioneers reported all these forms of acute damage, showing the range of doses they received in unfortunate single exposures.
Unfavourable Fpred within unfavourable Frec indicated chronic damage, favourable Fpred within unfavourable Frec indicated acute damage, and unfavourable Fpred within favourable Frec indicated vulnerability.
Long-term biologic storage of articular cartilage has proven elusive due to cellular degradation over time or acute damage during attempts at cryopreservation.
To better understand the role of the insula in maintaining abstinence, we examined quitting patterns in smokers with acute damage to their insula relative to other regions.
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