Preliminary results have demonstrated the feasibility of performing MST in the clinical setting, and there are suggestions that MST may have advantages over ECT in terms of subjective side effects and some measures of acute cognitive functioning.
After orthopedic surgery, acute changes in cognitive function, often referred to as postoperative delirium, occur in up to 89% of patients with preexisting dementia, and associate with poorer prognosis and even 2-fold greater risk for 1-year mortality compared to patients without dementia or delirium.
Acute hypoglycemia impairs cognitive function in several domains.
More research is also needed to identify the neurobiological mechanismsunderlying the impact of acute hyperglycemia on cognitive function.
What these findings do strongly indicate is that more research into the effects of acute hyperglycemia on cognitive function in children is warranted.
Other clinical endpoints include: inotrope score, length of ITU and hospital stay, LV ejection fraction, acute kidney injury, cognitive function, cardiovascular mortality, and hospitalization for heart failure.
Delirium (acute decline in cognitive function) is a common complication seen in older adults during and after hospitalization and may require more supervision to avoid errors in dosing.
In most cases, ARIAs produce no detectable clinical symptoms, but in some cases are associated with acute worsening of cognitive function.
Intranasal insulin administration appears safe, does not affect systemic glucose control, and may provide acute improvements of cognitive function in patients with type 2 DM, potentially through vasoreactivity mechanisms.
This study provides preliminary evidence that intranasal insulin administration appears safe in older adults with type 2 DM, does not affect systemic glucose control, and may provide acute improvements in cognitive function in older nondemented DM and non-DM patients.
This study found large individual differences in degree of impairment at different blood glucose levels, and there are likely numerous, unidentified variables that influence the impact of an episode of acute hyperglycemia on cognitive function.
