Sentence examples for acute blast from inspiring English sources

Progression to acute blast crisis is associated with additional mutations that might be independent of reciprocal ABL/BCR fusion protein expression, as suggested by the fact that p40ABL/BCR is not uniformly present in CML.

The number of neuropathological analyses of acute blast injury in humans are few.

The current situation reflects large knowledge gaps in understanding the pathobiology of acute blast neurotrauma and its aftermath.

At the physiological level, acute blast exposure has been associated with prominent vasospasm [ 46] and decreased cerebral blood flow [ 47].

The diagnosis of acute (blast cell) leukaemia in the presented calf was based on results of the haemogram, bone marrow aspirate and post mortem examination.

Freshly isolated human T cells and eFluor670-labeled CD33low OCI-AML3 target cells were co-incubated together with the modified hMSCs at an e t ratio of 1 1, resembling the in vivo conditions of AML patients in acute blast crisis (with low T-cell numbers).

The disease may then progress through an accelerated phase, or directly to an acute or blast phase when there are ≥30% blasts in the bone marrow or extramedullary blastic disease, and presents a very poor prognosis.

The recognition of acute leukemia blast cells in colored microscopic images is a challenging task.

In one model, preleukemic progression of a myeloproliferative disorder occurs in the only self-renewing cells of the myeloid lineage, HSC, but emerges from these clones when self-renewal is not shut down [or re-emerges] when these preleukemic or chronic phase leukemic HSC develop multipotent or oligolineage progenitors at acute or blast crisis phases of the disease [19].

FR- β is extensively expressed in acute AML blast cells.

In the acute phases, blast injury may produce large intraparenchymal and subarachnoid hemorrhages [ 46– 46].