The phrase "actual replication" is correct and usable in written English.
It can be used in contexts where you want to emphasize the authenticity or true nature of a replication process, often in scientific or technical discussions.
Example: "The study focused on actual replication of the experiment to ensure the results were reliable and valid."
Alternatives: "true replication" or "genuine replication".
This indicates that the replication/resumption profiles generated based on the common reference of 0-min samples are a fair representation of the actual replication profiles.
This assay could distinguish between actual replication errors and their removal by the DNA MMR system.
My first thought when reading the title of the paper was that this is about actual replication of crRNA.
Because the actual replication study of ~5K 5K cases:controls exceeds the sample size requirement, one might conclude that rs2273668 is a false positive.
However, sample size estimated using the follow-up OR value of 1.07 implies that the actual replication study was in fact drastically under-powered, and a much larger sample of ~41K 41K cases:controls (>20-fold increase) would be required to achieve 80% power at the 0.05 level (sample size calculation).
Further, despite the publication of dozens of studies of blue tit colour and many hundreds of statistical effects, the rarity of actual replication in the literature left insufficient evidence to support most of the frequently cited claims regarding the sexually selected role of plumage colour in this species.
However, these latter positive monocytes probably represented cells in circulation, rather than actual virus replication in the renal tissue.
The possibility of actual RNA replication by non-enzymatic thermal cycling is worth investigating experimentally, so, inasmuch as the present manuscript brings attention to such experiments, I find it useful.
Currently, we are searching by ultrastructural studies the possible presence of viral particles in the SF of positive cases for PCR analysis, which would indicate an actual local replication of viruses, rather than the passive carriage of viral DNA by blood leukocytes to the synovial space.
It is unknown whether possible chronic Q fever patients have actual persistence and replication of C. burnetii or whether there still is evidence of boosting.
With a larger sample size and replication of actual construction tasks, the implications for construction practitioners become more impactful.
