Combining inhibition of VEGF and EGF signaling might act additive or synergistically.
In contrast and as a positive control, the HC30 treatment affected statistically significant all investigated endpoints and it was demonstrated that the PSII inhibitors acted additive on various level of organization (Knauert et al., 2008).
Furthermore, MeJA and SA appear to act additive and exert their function via at least partially different JA -and SA-specific signaling routes.
A p-vector of the covariates Z ik in the additive hazards model acts additively on unknown baseline hazards, while it acts multiplicatively in the multiplicative model.
The differences in the crystal packing of these complexes were mainly due to the presence of the Nbs, which acted as additive binders to provide additional contact surfaces.
This pattern of results suggests that anxiety/depression and headache familial recurrence act as additive factors in oHs, while in migraine they might represent, together with psychiatric disorders in parents, interrelated aspects of a more complex relationship.
This pattern of results suggests that anxiety/depression and headache familial recurrence act as additive factors in non-migrainous headaches, while in migraine they might represent, together with psychiatric disorders in parents, interrelated aspects of a more complex relationship.
These mechanisms may act as additive protective elements for the brain, although trypanosomes will still be able to enter the central nervous system.
Although high, the concordance of monozygotic twins is not perfect, suggesting that environmental factors may act in additive or interactive ways with the genetic influence [ 5, 6].
In the present study, we also show that the mixture of five estrogenic chemicals acts in an additive manner in a glial cell model and that the additive action occurs with all three ERs.
In YUMAC melanoma cells, CI-isobol analysis showed that TSA acted synergistically while PXD101 acted at most additive when combined with Aza (Figure S2) This suggests that PXD101 may induce cell arrest by other mechanisms, independent of gene re-expression [41].
