The phrase "activity with a small" is not complete and lacks clarity in written English.
It could be used in contexts where you are describing a specific type of activity that involves something small, but it needs additional information to be fully understandable.
Example: "The activity with a small group of children was both fun and educational."
Alternatives: "task involving a small" or "event with a small".
Here, we demonstrate the graphene/Ni Fe layered double-hydroxide (RGO-Ni-Fe LDH) composite as highly active and durable electrocatalyst for OER, which exhibits excellent OER activity with a small overpotential (∼250 mV in 0.1 M KOH) based on the onset of catalytic current and stability.
As a result, the optimized Fe11%-NiO/NF electrode exhibited excellent OER activity with a small overpotential of 206 mV at 10 mA cm−2 and a low Tafel slope of 49.4 mV dec−1.
As the OER electrocatalyst, the Ni-Co graphene hybrids show a superior catalytic activity with a small Tafel slope of 67 mV per decade due to the synergy between the abundant active sites of the Ni-Co hydroxides and the conductive graphene coating, and a modest overpotential of 280 mV at a current density of 10 mA cm−2.
Gemcitabine-based chemotherapy for locally advanced or metastatic PDAC has only modest activity with a small survival benefit [3].
Coleman et al. [ 66], demonstrated the involvement of ROCK-I by inhibiting its activity with a small molecule inhibitor Y27632.
Interestingly, hnRNPA1 repressed IRES activity with a small, but significant reduction in the amount of luciferase produced.
We first observed that blocking NF-κB pathway activity with a small-molecule inhibitor, BAY-11-7082, in parental HCC1806 cells led to a significant reduction in anchorage-dependent colony formation and the migratory potential of these cells, which phenocopied the effects obtained in HCC1806-inducible MLknock-downown cells (Supplementary Fig. 14a and b).
Next, each of the 57 sequences was assessed for druggability that is defined as the likelihood of being able to modulate a target's activity with a small-molecule drug [27], [28].
Recently it was shown that in clear cell sarcoma (CCS), known for its chemoresistance, blocking c-Met activity with a small-molecule inhibitor (SU11274) or a neutralizing antibody to its ligand HGF/SF (AMG 102) CCS cell growth was significantly reduced in culture [ 40].
Apicidin, which like depsipeptide has some selectivity for class 1 HDACs (Bieliauskas and Pflum, 2008), did not generally mimic the drug sensitivity profiles of either depsipeptide or TSA, showing a narrower range of activity with a smaller distribution of IC50 values across the non-uveal melanoma cell line panel (compare Figure 2A with Figure 1C).
Others are like Rustic Pathways, a commercial operation that provides trips to Australia, New Zealand and Fiji and builds its trips around recreational activities, with a small amount of community service.
