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Most recently, mutations in the gene of ubiquitin-specific peptidase 8 (USP8) increasing its deubiquination activity were discovered in a high percentage of corticotroph adenomas.
Consequently, derivatives of EPO that lacked erythropoietic activity were discovered to reduce injury in many pre-clinical models associated with ischemia and inflammation.
After this early example of infection control through antisepsis, the next step was inevitable: when chemicals with antibacterial activity were discovered, they were soon used in the treatment of infected patients.
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A novel class of 2-amino-4- 2,4-dihydroxyphenyl thiazole 2-amino-4- 2,4-dihydroxyphenyl thiazole 2-amino-4- 2,4-dihydroxyphenyl thiazole 2-amino-4- 2,4-dihydroxyphenyl thiazole 2-amino-4- 2,4-dihydroxyphenyl thiazole
Amino acid amide racemizing activity was discovered in α-amino-ɛ-caprolactam (ACL) racemase (EC 5. 1. 1. 15) from Achromobacter obae.
Based on these SAR studies, a highly potent inhibitor of the Na+/Ca2+ exchanger, which showed single-digit-nanomolar activity, was discovered.
Also, an improved peroxidase-like activity was discovered for AgNC/MoS2-NS composite, in comparison with each of the constituents or natural peroxidase enzyme (HRP).
Mr. Herman also cited earlier statements by Mr. Al-Fadl to the F.B.I. that the jihad activities of Al Qaeda were built in the shape of a pyramid, "so that if one level of activity is discovered, the discovery is contained to that level in the organization".
However, potentially high denitrifying activity was discovered within the oxygenated Chukchi Shelf water during our summer expedition.
Mars' era of dynamo activity was discovered when the Mars Global Surveyor (MGS) spacecraft dropped to a low orbit during an aerobraking manoeuver and recorded quite high levels of crustal magnetization (Acuña et al. 1999).
Moreover, high seismic activity was discovered to be uniformly distributed in the region southwest of the Umehara fault, for a width of 20 km from the fault, although the seismicity is diffuse and does not show a clear fault plane (Fig. 5).
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