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Subsequent macrocyclization of the hexapeptide with FDPP under dilute conditions gave 3. Analogue 3 showed cytotoxic activity against P-388 cells, but its activity was much weaker than that of parent peptide RA-VII.
Gamma-band activity was much weaker though not absent before stimulus onset. Figure 2 C shows the change in spectral power during natural viewing when compared with the baseline, documenting a prominent gamma-band peak.
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In contrast to the Southern Ocean, polynya activity is much weaker in the Arctic Ocean, because the Arctic Ocean is surrounded by lands and thus divergent ice motion is greatly suppressed.
This activity is reminiscent of what has recently been reported by Patel et al [18], even though our activity is much weaker and requires weeks of exposure for detection.
However, VP2's apoptotic activity is much weaker than that of VP3.
Activity at Jólnir was much weaker than the activity at the main vent, and even weaker than that seen at Syrtlingur, but the island eventually grew to a maximum size of 70 m (230 ft) in height, covering an area of, during July and early August 1966.
In addition, because the GUS activity in PT2 was much weaker than PT1 in the leaves, the induction of GUS activity was visible in the PT2 leaves.
In general, the event-related neuronal brain activity in males was much weaker than in females.
Of note, the activity we observed for Ash2L/RbBP5 was much weaker compared to MLL1SET and required long exposure for detection (Fig. 2B).
In women, the inverse association between household activity and adiposity, though statistically significant, was much weaker than that in men.
In contrast, the basal activity of the exon −2c promoter was much weaker and unresponsive to TNFα stimulation in these cells.
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