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Within the Molecular Function ontology nine major groupings were found including phospholipid-hydroperoxide glutathione peroxidase activity, ethanolamine kinase activity, translation activator activity, ISG15 ligase activity, GTPase activity, protein disulfide isomerase activity, fatty acid transporter activity, protein binding, and NAD binding.
By reducing TOR activity (translation) and activating forkhead (gene expression), melted interacts within the insulin-signalling pathway to mimic the effects of nutrient deprivation [ 32].
Fewer genes were associated with apoptosis, transport, proteolysis, structural activity, translation and growth.
The overlapping genes are mostly associated with cell division, cell growth, kinase activity, translation, DNA integrity checkpoint and transcription regulation.
A clear outcome was that half of the translatome-specific terms (including translation translation regulator activity translation factor activity ribosome) were exclusively translation-related.
Uniquely overrepresented GO functions following medium U exposure were mainly associated with cellular metabolic and catabolic processes, transporter activity, translation and general stress response.
Similar(51)
As mediating activities, translation and interpretation occupy an important place in the normal linguistic functioning of the Chinese society and are taught and learnt as a language skill in tertiary education.
It will also enhance the future potential for biobank-driven translational activity; particularly, translation into population level public health.
We propose that elucidation of the mechanism by which hTRM9L activity affects translation and paromomycin sensitivity may allow us to exacerbate this translational error phenotype for therapeutic purposes.
One possibility is that the eIF4AIII-dependent helicase activity increases translation efficiency by changing the local geometry of the RNA.
We therefore chose to use the Eμ-Myc lymphoma model to assess the anti-cancer and chemosensitization activity of translation elongation inhibitors.
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