Sentence examples for activity of fact from inspiring English sources

However, if this were the case, we would expect any changes in the Spt16- Pob3 dimer interface to be subtle, specifically affecting the activity of FACT in transcription-dependent nucleosome assembly rather than in a more general histone chaperone role.

These data are also consistent with the ascribed histone chaperone activity of FACT, which destabilizes the histone octamer and facilitates the release of a single histone H2A H2B dimer from the nucleosome to promote passage by transcribing Pol II (Orphanides et al, 1998, 1999; Belotserkovskaya et al, 2003).

Furthermore, chromatin transcription by mammalian Pol I appears to require the histone chaperone activities provided by nucleolin (Angelov et al, 2006; Rickards et al, 2007) and nucleophosmin (B23; Okuwaki et al, 2001; Murano et al, 2008), as well as the activity of FACT.

Laurie Anderson has a disarming way of making intense levels of activity seem matter-of-fact, even laid-back.

These activities include distribution of fact sheets to county emergency management agencies, fire departments, other first responders, and industries; and presentations to municipal water directors, engineers, and hotel/motel swimming pool owners and operators.

Yet, four seasons into The Walking Dead, we watch as those still living kill the zombified deceased and accept the skewering of skulls as a matter-of-fact activity akin to the brushing of teeth.

P. aeruginosa strain 15442 was the most sensitive inhibitory activity of SP1, in fact, at a concentration of 3.1 mg/ml, a value of about 73% inhibition was observed, while for the other strains the inhibition values were of around 50% (Figure 5). Figure 5 Interference with biofilm formation of SP1 against reference staphylococcal and P. aeruginosa strains.

Although the design of the study does not allow for confirmation that DHA increased the basal activity of chemotherapy, the fact that both TTP and OS were vastly different according to the level of DHA incorporated indicates that the addition of DHA to chemotherapy had a beneficial effect when highly incorporated.

While colloidal exclusion almost certainly accounts for loss of activity, the fact that activity reverts to zero rather than flat-lining at an apparent maximum is intriguing.

The gradient salt elution profiles from the Mono-S column were similar for FACT subunit SSRP1, Pol I subunit hRPA19 (and9) and Pol I transcriptional activity, suggesting the co-purification of FACT with Pol Iα.

On the other hand, they could also provide a rationale for novel strategies of enhancement of chemotherapy activity: in fact, Cox-2 selective inhibition could be a feasible and not toxic tool to increase chemotherapy effectiveness.