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Interest is growing in the search for natural compounds active against pathogenic trypanosomatids, resulting in several reports on the biological activity of essential oils (EOs) or their main constituents on these protozoa [ 6, 18– 20].
To the best of our knowledge, the potential hepatoprotective activity of essential oil from rosemary, which contains monoterpenes as its main active compounds, has not been previously tested in vivo.
Politeo et al. reported the following sequence in terms of antioxidant activity of essential oils: O4 > O5 > O6 > O2 [57].
Antifungal activity of essential oils according to their major components was as follows: phenols > alcohols > aldehydes > ketones > ethers > hydrocarbons [32].
The antioxidant activity of essential oils was measured using the ferric reducing antioxidant power (FRAP) assay [28, 29].
The antioxidant activity of essential oils obtained by hydrodistillation was also low and not comparable to ethanol extracts.
Hydrodistillation show no statistically significant differences in antioxidant activity of essential oils obtained from four different fractions (one group of letter).
Regarding the correlation between Fusarium mycotoxins expressed by FUMO content and antioxidant activity of essential oils, there was not recorded a good correlation.
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A plethora of studies is available which conclude antinociceptive activity of essentials oils of medicinal plants [ 40- 42].
Due to antioxidant and antimicrobial activities of essential oils (Burt 2004), they may make the film become active.
The metal (Fe2+) chelating and DPPH radical-scavenging activities of essential oils were measured as previously described (Dinis et al. [1994]; Kirby and Schmidt [1997]).
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