Moreover, PKA phosphorylates pyruvate kinase directly, a modification that renders its activity less dependent on allosteric activation by FBP (Portela et al. 2002, 2006).
It may be hypothesized that low intensity anxiety, such as worry and tension, as measured by HADS-A, activates proinflammatory cytokines or neurohormonal stress activity less than diagnostic categories of anxiety, such as panic disorders and agoraphobic disorder.
Giving too much time runs the risk that "students have moved on to non-class topics," but "cutting off the activity while students are actively working on it may make the activity less effective".
The binding of Ca2+ ions to GCAP1 is thereby reduced, making the cyclase activity less responsive to Ca2+ concentration and leading to constitutive activation of retGC1 by the mutant GCAP1 [9].
Less traffic, less noise, fewer people, less activity, less momentum, less certainty, less joy.
WHOEVER coined the term "surfing the Internet" clearly had an impoverished sense of adventure; it would be hard to imagine an activity less like surfing than sitting motionless in a chair, waiting for Web pages to download.
It is as if the policy mood was a thermostat: signalling the need to cool things when they get 'too hot' under Labour by supporting less government activity – less spending, less welfare and less regulation.
At the center of all this activity, less than a direct source but more than a mere reference — and largely invisible — was Marcel Duchamp (1887-1968).
Yes: they signal to polluters that the environment is valuable, and a tax system that includes them will distort economic activity less than one that does not.
How else to explain his waste of the lead paragraph in "Is Small and Cute What Surfers Want?" (State of the Art, Dec. 21), when he said, "It would be hard to imagine an activity less like surfing than sitting motionless in a chair, waiting for Web pages to download".
The link will even speed the geographical "rebalancing" of the economy that the coalition has pledged to engineer, which will see activity less concentrated in the South East.Not everyone is impressed.
