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Enzymatic inhibition of histone deacetylase (HDAC) activity is emerging as an innovative and effective approach for the treatment of cancer.
A growing paradigm of microRNAs regulating gene activity is emerging.
In addition, the selective inhibition of 11β-HSD1 actisity is emerging as an exciting, novel therapeutic approach in type 2 diabetes and the metabolic syndrome (40, 42).
The genetic manipulation of stomatal activity is emerging as a promising approach to reduce the water requirement of crops, and to enhance productivity under stress conditions [ 2].
Indeed, selective inhibition of 11β-HSD1 actisity is emerging as an exciting, novel therapeutic approach in type 2 diabetes and the metabolic syndrome (40).
Apigenin, a natural plant flavonoid with antiproliferative activity, is emerging as a promising compound for cancer prevention and therapy, but its mechanism of action remains unclear.
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Their wish to improve education is evident and I welcome some of their actions – the commitment to the pupil premium, maths hubs and some of the work on special needs – but beyond that, three more significant areas of activity are emerging.
Inhibitors of histone deacetylase activity are emerging as a potentially important new class of anticancer agents.
Candidate biomarkers identifying susceptible individuals or indicating disease activity are emerging, [ 2] along with a better understanding of outcomes in clinical trials [ 3].
Studies on the association between neighbourhood walkability and neighbourhood-based physical activity are emerging, 78 79 but these have a high-respondent burden and are not generally feasible for national-scale studies like that presented here.
Given the increasing resistance of S. pneumoniae to the traditional first-line agents employed in CAP treatment, recent fluoroquinolones with improved antipneumococcal activity are emerging as important therapeutic options.
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