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Jang, T. et al. 5′-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.
Thus, Src activity is elevated in premalignant UC epithelia, which is at greatest risk for developing cancer.
On the other hand, 3MST activity is elevated in human neoplastic cell lines43 and erythrocytes from patients with polycythemia vera44, so selective 3MST inhibitors might have therapeutic value for these diseases.
Positron emission tomography using [18F]fluorodeoxyglucose (FDG) has shown that metabolic activity is elevated in the frontal cortex of cocaine addicts within 1 week of abstinence, but it decreases with longer periods (Volkow et al, 1991).
Biochemically, the mutant protein is not capable of dimerization, and enzymatic activity is elevated in the embryos, thus a demonstration of the in vivo role of LIS1 as a subunit of PAF-AH.
This NOX is stimulated by calcium release [18], and as such its activity is elevated during muscle contraction.
Since NE activity is elevated in CF patients and correlates with disease progression, development of NE inhibitors has been of prime interest [157, 158].
Instead, microglial movement after SD is enhanced when synaptic activity is elevated.
MAPK activity is elevated in all three cancer cell lines examined (data not shown; [ref.4]).
The data demonstrate that GSNO-R activity is elevated in the female mouse lung when compared to the male.
However, that rac activity is elevated in SSc cells and that this is required for enhanced Akt activity in SSc fibroblasts has not been shown.
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CEO of Professional Science Editing for Scientists @ prosciediting.com