The phrase "activity in the advanced" is not correct and does not convey a clear meaning in written English.
It may be intended to refer to activities that are advanced in nature or complexity, but as it stands, it lacks clarity and context.
Example: "The research team is focusing on activity in the advanced stages of the project to ensure timely completion."
Alternatives: "advanced activities" or "activities at an advanced level".
Gefitinib (IRESSA), an epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor, has antitumour activity in the advanced non-small-cell lung cancer (NSCLC) setting.
Owing to the lack of association between proinflammatory cytokines and CYP2C19 activity in the advanced cancer patients, the samples were also analysed for the levels of growth hormone.
There was preliminary evidence of an association between BMI and CYP2C19 activity in the advanced cancer patients; according to the standard cutoff for BMI, among those with low BMI (<25) 62% (8 of 13) were PM compared with 22% (4 of 18) in patients with a high BMI (>25) (P=0.03).
Our data obtained in patients with SAD dementia also indicate that CSF BACE1 activity does not parallel brain BACE1 activity, at least in the advanced stage of the disease.
Anti-EGFR monoclonal antibodies have demonstrated activity in the therapy of advanced colorectal carcinoma and in a variety of epithelial tumor types, including head and neck cancer and non-small cell lung cancer (NSCLC).
This provides a sound argument for low aggrecanase activity in the discs with advanced degeneration.
We conclude that zindoxifene in the doses used in this study has only marginal therapeutic activity in the treatment of advanced breast cancer.
The taxanes paclitaxel and docetaxel show good activity in the management of advanced ovarian cancer when used in conjunction with platinum agents.
First, at the time of the trial's conception, both agents had shown activity in the treatment of advanced breast cancer.
The combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN-alpha) has reported activity in the treatment of advanced colorectal carcinoma.
Cetuximab is an epidermal growth factor receptor (EGFR -directed IgG1 chimEGFR -directedl antIgG1y showing antitumour achimericin the treatmonoclonalvantibodylorectal cancer.
