Sentence examples for activity in a tissue-selective from inspiring English sources

Tibolone regulates estrogenic activity in a tissue-selective manner.

We searched for genes expressed in a tissue-selective manner.

We found only 59 transcription factor genes expressed in a tissue-selective manner.

This unique steroidal compound is converted in a tissue-selective manner to estrogenic, progestogenic, and androgenic metabolites.

Raloxifene belongs to the family of selective estrogen receptor modulators (SERMs) that display agonistic or antagonistic activity in a tissue-dependent manner [ 33].

In vivo MC1568 shows an apparent tissue-selective HDAC inhibition.

Many complex disorders are driven by a coupling of housekeeping (universally expressed in all tissues) and tissue-selective (expressed only in specific tissues) dysregulated pathways.

In addition, Hsiao et al. [ 15], who created a compendium of tissue-selective genes based on microarray data, described five of these genes as "vulva-selective".

On PND30, DZN treatment enhanced AC activity in a sex- and stimulant-selective manner.

Interestingly, each of the TR agonists tested above exhibited significant tissue-selective activities, as indicated by the colored arrows in Figure 4c.

Subsequently, both procedures are compared in a simulation study and the Bayesian procedure is used to find the tissue-selective genes for a panel of 22 tissues.