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For example, efforts to uncover signaling activity governing metastasis from lung carcinomas found that a lung WNT signaling program was functional in promoting meta-stasis from lung cancer lines and prognostic of lung cancer patients in clinical databases [ 52].
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The process and pathways involved in hemostasis and thrombosis are complex and have overlapping and intersecting limbs with the overall activity governed by the balance of activators and inhibitors.
With managed and restricted activity governed by law, and supported by local fisherman and the public, there is the potential that further reefs might recover in other newly protected areas around the UK such as the coast of south Devon, the Isle of Wight and large parts of the North Sea.
The intuitive appeal of various principles may vary with the range of activity governed by the legal rule or institution.
Though the president was a gracious loser, he far preferred not to overdraw on those particular reserves of graciousness -- whether at golf or tennis or, especially, horseshoes, an activity governed by a mysterious "Committee" to which only the president seemed to have access.
eIF2B activity governs the rate of global protein synthesis in the cell.
Another important function of ANG is the ribonucleolytic activity governed by the catalytic triad residues His13, Lys40 and His114.
These data thus demonstrate that the oncogenic activity governed by cyclin D1b is independent of aberrant expression in later phases of the cell cycle.
Importantly, AP-1 activity governs the transcriptional induction of cyclin D1 to promote the enhanced proliferation of established breast cancer cells [ 1].
It has been shown that composite disease activity indices have special merits in following patients, that disease activity governs the evolution of joint damage, and that disability can be dissected into several components – among them disease activity and joint damage.
Thus, the regulation of Pah1 activity governs the synthesis of TAG, the pathways by which phospholipids are synthesized, PA signaling, and the growth of the nuclear/ER membrane (Carman and Han 2008).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com