The phrase "activity for the initial" is not correct and lacks clarity in written English.
It may be intended to refer to an activity related to an initial phase or step in a process, but it is incomplete and ambiguous.
Example: "We need to plan an activity for the initial phase of the project to engage the team."
Alternatives: "task for the beginning" or "exercise for the first stage".
Incubations in the presence and absence of proteinase inhibitors revealed at least an aminopeptidase M activity for the initial N-terminal truncation of tryptophan (W130) and a putative glutaminyl-peptide cyclotransferase activity for the resulting intermediate starting with the bared glutamine residue (Q131).
Interestingly, if a model developer uses a range of descriptors to create a perfect fit between structure and observed activity for the initial group of chemicals with known experimental results (the 'training set'), this can result in the model producing poorer predictions for other related chemicals.
We used in vitro Pol-β-directed strand-displacement activity assay for the initial screening of the compounds.
Once an intervention proves to be effective in a given context, scaling up or replicating that intervention will seldom require the same research activities required for the initial trial.
One possible explanation is that removal of additional components of the SMN complex may not enhance Smn-related phenotypes since SMN activity is critical for the initial steps in SMN complex assembly.
However, our data show that HDAC6 activity is necessary for the initial development of the axon in hippocampal neurons in conditions where glial cells are not present or their role is reduced, as it happens in early development.
For this model, we assume that the physiological damage arising from regular muscular activity is responsible for the initial mechanical damage.
Thus, to determine the potential for CDK4 activity during the initial 8 h of stimulation, activated B cells were analyzed for levels of cyclin D2 (the predominant cyclin D family member in B cells) [27], [28].
For the energy demand to be met the diet must provide sufficient energy; its main source for muscle activity sustaining the initial anaerobic contraction is glycogen.
For the activity measurements, the initial rates of pNPG (0.01 – 20 mM) hydrolysis were measured in 50 mM sodium acetate buffer (pH 5.0) containing 0.1 g l-1 BSA in a total volume of 0.9 ml.
In contrast, E364 is in proximity to the docked substrates in the newly identified substrate-binding pocket Site II, implying that Site II might be the actual substrate-binding site for PO activities, at least for the initial substrate binding, which is independent of the canonical 'placeholder' position.
