Sentence examples for activity blocking from inspiring English sources

This would suggest: 1) that cytokines impair IRS-1 activity, blocking anabolic insulin signaling cascade with less activated mTOR and 2) that the molecular mechanism of leptin-mediated impairment of insulin signaling is similar in both skeletal muscle and lymphocytes.

Because phosphorylation is essential for STAT3 biological activity, blocking the upstream protein kianses responsible for STAT3 activation also represents a rational approach to prevent carcinogenesis.

As we were about to enter the Lincoln Tunnel, there was police activity blocking the lanes and an officer directing all cars to a toll lane that was an "E-ZPass Only" lane.

Chlorpyrifos inhibits acetyl cholinesterase activity, blocking neuronal activity and paralyzing the animal.

Endogenous peroxidase activity blocking and immunoincubation was performed as described before using polyclonal rabbit 758 antibodies against zebrafish Fmrp [27].

In those cells, highly expressed cki-1 strongly represses the low CYE-1/CDK-2 activity, blocking proliferation and permitting differentiation into DTCs.

We also showed that inhibition of PI3K activity blocked Akt activation in TRAIL resistant cell lines.

Heat- inactivation of WT-CF proteolytic activity blocked its ability to activate ERK1/2 or JNK phosphorylation (Fig. 2E-F).

Interestingly, we found that inhibiting TβRI kinase activity blocked TGFβ-induced Smad2/3 but not ATF2 activation.

Heat- inactivation of WT-CF proteolytic activity blocked its ability to peel the cells.

Conversely, a point mutant of Pias1, that lacks ligase activity, blocked the endogenous expression of Nkx2.2.