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The %DRs were 33.02 and 33.33 % for the doses of 7.5 and 10 mg/kg, respectively (Table 3).> -wrap-foot> Standarddard error NA: Not analysed %DR: Percentage of damage reduction Different letters indicate statistically significant differences (p < 0.05; ANOVA/Tukey) AMS049 exhibited no mutagenic activity at any dose or time of evaluation.
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Compounds 3a, 3c, and 3e exhibited ≥90.3% activity at a dose of 500 mg/L.
The first peak (the PS-I fraction) induced agglutinating activity at a dose of 6.25 μg/ml, while the second peak (the PS-II fraction) induced this activity at a higher dose of 200 μg/ml (data not shown).
The diyne 2 also had potent inhibitory activity at a dose of 5 and 2.5 μg/CAM.
The superior pharmacokinetic profile of CHN translated into superior chemosuppressive activity at all dose levels relative to CHS.
Finally, PL loaded nanoemulsions showed marked anti-tumor activity at a dose of 10 mg/kg in melanoma tumor bearing mice.
These results showed that biochanin A has potential antihyperglycemic activity at a dose of 10 mg/kg bodyweight in streptozotocin induced diabetic rats.
Furthermore, 1b and 2d showed significant antiamnesic activity at a dose of 1.0 mg/kg as compared to the reference compounds piracetam and rivastigmine.
The aqueous extract of the plant showed prominent activity at a dose level of 200 mg/kg.
BUN values and ALT activity at a dose of 1000 mg/kg was significantly increased compared to the controls.
TAM induced UWW and LEH in a manner consistent with its partial-agonist activity at a dose equipotent to EE.
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