Regulation of Hox gene expression during mammalian development is complex and involves regulatory RNAs and proteins whose activities orchestrate the establishment and subsequent maintenance of the AP Hox expression patterns (for review, see Chopra 2010).
Neuronal activity orchestrates the proper development of the neuronal circuitry by regulating both transcriptional and post-transcriptional gene expression programmes.
Moreover, it should be noted that cyclin B1-Cdk1 activity orchestrates mitosis and therefore drives the changes that result in the inhibition of CME at a higher level.
Although the mechanisms by which these glycosyltransferases may participate in the regulation of pluripotency and differentiation of hPSCs have not been well characterized, it is likely that their enzymatic activity orchestrates the functions of many pluripotency-related signaling molecules.
Taken together, these results demonstrate that TGFβ activity orchestrates cell flattening by triggering the N pathway and that, once this pathway is activated, either of the pathway regulate common targets and/or Notch fulfils some of the TGFβ requirements.
A well-established cascade of transcription factor (TF) activity orchestrates adipogenesis in response to chemical cues, yet how cell-intrinsic determinants of differentiation such as cell shape and/or seeding density inform this transcriptional program remain enigmatic.
Transcriptional activation orchestrated by the transcription factors AP-1/c-FOS, VDR, and NF-kB, was modulated by increased activity of TLR, AR and ephrin receptors.
How much of P2's activities were orchestrated by Gelli was impossible to say.
