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We studied the activities of tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1) and the levels of tPA antigen (a marker of endothelial dysfunction) in 551 subjects with normal glucose tolerance in 1990 in relation to incident diabetes during nine years of follow-up.
18F-2-Fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography (PET) provides information about the metabolic activities of tissue cells and is widely used in cancer management.
Cyclosporine A induced renal damage was evident from the decreased activities of tissue marker enzymes (alkaline phosphatase, acid phosphatase, lactate dehydrogenase, aspartate transaminase and alanine transaminase) and decreased activities of ATPases (Na+, K+-ATPase, Ca2+-ATPase and Mg2+ ATPase).
Administration of B[a]P (50 mg/kg, p.o). to mice resulted in increased lipid peroxidation (LPO), proinflammatory cytokines (TNF-α, IL-6 and IL-1β) with subsequent decrease in activities of tissue enzymic antioxidants (SOD, CAT, GPx, GR, GST) and non-enzymic antioxidants (GSH and Vit-C).
SERPINA3K specifically binds to tissue kallikrein, forming a covalent complex and inhibits proteolytic activities of tissue kallikrein [6].
The enzymatic activities of tissue matrix metalloproteinases were measured by performing gelatin zymography in brain samples.
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The antioxidant activities of tissues of H. pogonocalyx collected in different seasons are presented in Table 2.
Rodero, Poupel, Loyher et al. investigated the activities of tissue-resident monocytes found in the lungs of mice.
These data suggest that ETC activities of tissues of aging complex organisms may exhibit tissue-specific physiological characteristics of longevity.
Extracellular HMGB1 is known to bind to several components of the plasminogen activation system and to enhance the activity of tissue plasminogen activator [ 29] and matrix metalloproteinases 2 and 9 [ 30].
Profibrinolytic action allows the activity of tissue plasminogen activator (endogenous tissue plasminogen activator), by inactivating plasminogen activator inhibitor 1 and thrombin activatable fibrinolysis inhibitor.
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