Sentence examples for activities of gaps from inspiring English sources

Alterative activities of GAPs may contribute to tumorigenesis by promoting tumor progression and growth [8].

The transient activation of Rac1 by GEF s) may be important in allowing dynamic membranes to promote contacts between cells, but the further establishment of initially weak cell-cell adhesion may require dampening of membrane dynamics by rapid down-regulation of Rac1 activity following activation of GAP s).

Notably, mitochondria in vivo behave as a network of functionally coupled oscillators, which maintain a high level of coordination throughout the tissue via the activity of gap junctions.

To test the activity of GAP-stimulated GTPase activities, we used NF1-333 and RanGAP with their cognate GTPase Ras and Ran, respectively.

To decrease the GAP activity of ArhGAP44, we substituted a conserved arginine in the catalytic cleft with a methionine, which was shown to reduce but not eliminate the enzymatic activity of GAP proteins (Muller et al., 1997; Graham et al., 1999).

It will be interesting to determine whether Plk1 is controlling contractile ring formation by regulating the interactions or activities of Rho-GAP and Rho-GEF in vertebrate cells.

Unexpectedly, these mutants maintained a high level of activity on gapped substrates.

Potential positive impacts of clinical guidelines include: improved quality of clinical decisions, reduced variation in care, support for other quality improvement activities and identification of gaps in research evidence.

They have potent anticarcinogenic properties, including antioxidant activity, stimulation of gap junction intercellular communication, induction of detoxifying enzymes and inhibition of cellular proliferation.

Thus, the activation state of the Rho GTPases depends on the balance of activities of GEFs and GAPs.

GDIs inhibit the activities of GEFs and GAPs only by sequestering Rho GTPases.