Despite of extensive clinical applications of TCM formulae, knowledge about their pharmacological activities, mechanisms of action and cellular targets remains limited.
For this purpose we used computer program PASS [19, 20], which predicts more than 7000 pharmacological activities, mechanisms of action, mutagenicity, carcinogenicity, teratogenicity and embryotoxicity on the basis of structural formulae of compounds.
By taking the activities, mechanisms, benefits, and limitations of antitumor-related artemisinins into consideration, we provide a significant sight for the current and future development in this promising field of cancer drug discovery.
PharmaExpert software analyzes the relationships between biological activities ("mechanism-effect(s)" and "effect-mechanism(s)"), identifies probable drug-drug interactions, and searches for compounds acting on multiple targets [ 33- 43].
This realist review will address an existing knowledge gap by summarising evidence on how context impacts activities, mechanisms and effectiveness of care transition interventions.
Since the project was implemented as a programmatic intervention, tracer team activities, mechanisms of tracing, modes of transportation, and health facility placement varied by subdistrict.
While UNICEF monitoring mechanisms were in place to monitor implementation of activities, mechanisms for monitoring practice and performance at the local government and partner levels have yet to be incorporated and strengthened.
The effect of the pH value of the reaction medium in the antibacterial activity mechanism has been considered.
The photocatalytic activity mechanism of nano-TiO2 has been extensively studied in the literature [8 13], and the basic photocatalytic mechanism is shown in Fig. 1.
Open image in new window Scheme 2 Enhanced photocatalytic activity mechanism of Sm ZnO Ag Nps in the presence of LED/solar lights.
