All patients should have recorded headache diaries for 4 weeks (baseline phase) before enrolment to assess disease activity (disease duration, headache degree, and attack frequency).
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The presence of Pg DNA did not influence disease activity, disease disability or positivity for autoantibodies.
Low-activity disease was defined as persistence of minor symptoms (for example, arthralgia or myalgia) [ 24].
The activity of disease was evaluated by calculation of 28-joint Disease Activity Score (DAS28) [ 34].
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PON1 activity and disease severity scores were inversely correlated.
Disease activity was evaluated using Disease Activity Score 28 (Dand8) and C-reactive protein (CRP).
Disease activity was measured using the disease activity score (Disease Activity Score based on 28 joints [DAS28]) and serum C-reactive protein.
Disease activity was assessed by the disease activity score in 28 joints (DAS28; erythrocyte sedimentation rate (ESR), low disease activity state (LDAS) ≤3.2; remission <2.6), 7 and by the simplified disease activity index (SDAI; low disease activity ≤11.0; remission ≤3.3).
