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For instance, the phytoestrogen genistein and the xenoestrogen bisphenol A, which exert estrogen-like activities binding to and activating ERα [ 9, 59], displayed the ability to bind to and activate GPER signaling [ 9, 27, 60].
In addition, it has been reported that cell surface-associated EF-Tu of many distinct bacteria show multiple activities binding to various mammalian proteins including mucin (Lactobacillus johnsonii) [57], fibrinogen (Mycoplasma pneumoniae) [58], plasminogen and factor H (Pseudomonas aeruginosa) [59].
In addition to having different biologic activities, binding affinity may skew interpretation of antibody target engagement studies in humans.
In contrast to these negative regulations of AGO1 activities, binding of miR168 by AGO18 in infected rice plants directly boosts AGO1 accumulation.
Only 4 significant GO molecular functions were observed, and they were involved in general binding activities (binding, protein and ion binding, catalytic activity, FDR & 0.05).
Results: Our study revealed that the chemically diverse compounds bound to ERs via varied sets of protein ligand interactions, reflecting their differential activities, binding affinities, and specificities.
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The toxic compound is able to inhibit enzyme activity binding to some positions around its active site.
The MCP-1 HABPs 33387 and 33397 also presented high activity binding to HepG2 cells.
High activity binding peptides to human red blood cells have been identified in this protein.
The E4P-bound structure shows that the location of the inhibitor (of cytokine activity) binding site of human AMF is very similar to those of the inhibitor (of enzymatic activity) binding sites of PHIs.
Four and three specific high activity binding peptides (HABPs) to the A549 alveolar epithelial and U937 monocyte cell lines were found, respectively.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com