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The effect of MRN on ATM and its activity is likely to happen on multiple levels, as well as recruitment of ATM by Nbs1 to the sites of DNA double-strand breaks (DSBs) (Falck et al, 2005), the MRN-dependent DSB unwinding and tethering activities are essential for efficient ATM activation (Costanzo et al, 2004a; Lee and Paull, 2005).
Yet those activities are essential; no company can neglect them.
Since such activities are essential for college admission, what parent will say no?
Creative activities are essential for a company to get off the ground.
Biofilms, which are formed by bacterial activities, are essential components of biofouling.
When even air-conditioning can't beat the city heat, outdoor activities are essential to staying sane.
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The adequate design of the partnership between companies in this type of outsourcing activities is essential.
Involving partners and understanding the importance of their activities is essential for enterprise agility.
Whatever the reason, Cameron and his advisers bungled in not grasping earlier in the week that full disclosure of his past offshore investment activities was essential and unavoidable.
Effective campus-wide support, via offices with well-planned and -advertised activities, is essential.
A correct balance between kinase and phosphatase activities is essential in maintaining cell homeostasis (Hunter, 1995).
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