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These numbers are likely underestimated, considering the fact that linker fragments can also be missing and the connectivity patterns may not allow for the correct reconstruction of the topology of target actives, leading to non-reconstructible cases.
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These data are consistent with the model that individual mitochondria are more active, leading to a tissue with normal OXPHOS activity.
When Nrf2 is constitutively activated (as in Keap1 knockdown or knockout), HDAC4 is fully reduced and active, leading to enhanced transcription of NOX4, and higher levels of ROS.
We suggest that AWB neurons may be inhibited by AWA and, when odor is removed, AWA is no longer active, leading to a release from inhibition and an increase in AWB activity.
Currently, there is no report showing how oxidation affects cysteine synthase activity, it is possible that oxidized form of the enzyme is more active, leading to synthesis of more cysteines and increased amount of GSH in the defense against Pst.
Finally, the activity test showed that the engineered PAH secreted by L. plantarum CM_PUJ411 is active, leading to a reduction in l-Phe and an increase in l-Tyr levels, respectively.
Tuggle, 36, was a five-time Pro Bowler and the NFL's active leading tackler with 1,830.
Before the season, conventional wisdom said the San Diego Padres would be active leading to the nonwaiver trading deadline.
The Mn/Ce catalyst was the more active leading to high TOC conversions (99.4%).
When hormones surge in puberty, the amygdala grows in size and becomes more active, leading to rash and emotional behavior.
But genes are fused in the process, and proteins that normally are tightly regulated become constitutively active, leading inexorably to disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com