Exact(17)
However, the ABCA1 transporter actively transports also other lipids, namely cholesterol, phosphatidylcholine, phosphatidylserine, and SM [62].
A brain microdialysis study revealed that this transporter actively transports oxycodone and diphenhydramine into the brain, and their unbound concentration in brain interstitial fluid (ISF) is 3- to 5-fold higher than that in blood [ 10, 11].
P-glycoprotein is an efflux transporter that actively transports lipophilic drugs from the intracellular to the extracellular domain.
System A is a ubiquitous Na+-dependent transporter that actively transports small, zwitterionic, neutral amino acids with short, unbranched side chains, such as alanine, serine, and glutamine (21).
System A is a Na+-dependent amino acid transporter that actively transports small, zwitterionic, neutral amino acids with short unbranched side chains and the synthetic amino acid α- methylamino)isobutyric acid (MeAIB) [5].
This cell line is commonly used for recombinant protein and after expressing human kidney ABCC6 cDNA on isolated membranes of Sf9 cells using a viral vector (such as a baculovirus vector or pBluescript SK vector) it was shown that human ABCC6 has a high capacity drug-stimulated ATPase activity and that it actively transports leukotriene C(4) and N-ethylmaleimide S-glutathione (NEM-GS) [ 19, 93].
Similar(43)
The SfuC-Fe complex associates with the ATPase (SfuA) and permease (SfuB) components of the tripartite ABC transporter complex to actively transport iron into the cell.
In Buchnera's closest free-living relative E. coli, β-alanine is actively transported via amino acid transporter cycA [ 44].
Exogenous taurine was reported to be actively transported by a taurine transporter (TauT) into cells 10, 11, 12.
ABC transporters act in metabolism by actively transporting xenobiotics and/or their metabolites into or out of tissues.
Its metabolite, 1-methyl-4-phenylpyridinium (MPP+), is actively transported into DAergic neurons by the dopamine transporter.
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