Sentence examples for active signaling from inspiring English sources

(A ) When Insulin receptor or Insulin-like growth factor receptor is active signaling through AKT inhibits Foxo transcription factors and activates mTOR.

The identification of circulating miRNAs, mainly delivered by cell-secreted MVs, as stable and active signaling molecules opens a new field of research in intercellular and interorganelle signal transduction.

It was previously found that subcutaneous injection of BmK I caused release of various biologically active signaling molecules including proinflammation cytokines and brain-derived neurotrophic factor [39 41].

Overexpression of several constitutively active signaling molecules abrogates the dependence of these cells on IL-3 [9].

Here we define the specific function of HH signaling in the ureteric cell lineage during murine kidney development, in genetic models of deficient or constitutively active signaling.

DCNs express both Delta and Notch and the proteins appear intracellular, indicative of active signaling.

It is likely that this complex regulation is also dependent of the in vitro context (growth factors, monolayer or 2D culture conditions) and others active signaling cascades [ 48].

A critical issue is how to relate transiently active signaling pathways with sustained changes evoked by permanent alterations in prion proteins.

However, Zhu et al relied heavily on overexpression of constitutively active signaling proteins, AMPA-Rs or both, which may not reflect the endogenous situation.

Attachment of monoubiquitin to membrane proteins serves a signal for internalization of the TLR into the endosome, the site of active signaling.

Redox-active signaling endosomes were first discovered by Li et al. in 2006 and were named "redoxosomes" by Oakley et al. in 2009.