Sentence examples for active run in from inspiring English sources

Having any of these attributes was significantly associated with greater drug vs. placebo differences on symptom improvement: female, patients being middle aged, increasing proportion of patients on placebo, excluding all patients from centers with high placebo response regardless of active treatment response, using active run in periods and including self-report measures.

The rationale for the active run-in periods is explained in the Discussion.

The active run-in period of PARADIGM-HF served two main functions.

The active run-in was conducted to provide data on the short-term effects of fenofibrate therapy on cholesterol levels for all randomized patients.

All received dietary advice, followed by a 6-week single-blind placebo run-in, then a 6-week active run-in period before randomization.

Upon the patients' return after the placebo period, consenting eligible patients were then entered into a 6-week single-blind active run-in period.

Thus, studies with crossover design or an active run-in phase before the treatment period were not included in the evaluation of the IOP-reducing effect.

Baseline eGFR was taken as the mean of two measurements before the active run-in phase (visits 1 and 3, median 72 days apart).

Of the 13 900 patients screened in study clinics, 75.9% (10 553) proceeded to enter the placebo run-in phase and 73.4% (10 203) the active run-in phase, and ultimately 9795 (70.5%) patients were randomized.

After a 6-week active run-in period, 11,140 patients with type 2 diabetes were randomized to treatment with a fixed combination of perindopril and indapamide or matching placebo, in addition to current therapy for CVD risk factor control.

Further, the active run-in period was to determine to what extent any long-term clinical benefits of treatment correlate with the short-term effects of the drug to modify different lipid fractions.