Sentence examples for active polymerase from inspiring English sources
The gene expression probability is given by: 1 The numerator in this function represents all the transcriptional states in which polymerase is bound and transcription can be active: polymerase on its own, activator and polymerase bound, or repressor and polymerase bound.
The recruitment of CBP by CREB to the promoter of a CREB target gene then induces the assembly of an active polymerase II transcription complex, thus leading to target gene activation [ 55].
In contrast, cells with limited number of active polymerase could not.
There is a strong positive correlation between trimethylation of H3K4, transcription rates, active polymerase II occupancy and histone acetylation [12].
It is of considerable interest to know the mechanism by which the active polymerase is chosen at any time or place during DNA synthesis.
However, there is evidence that only one polymerase is bound to a pocket at one time, and that this is the active polymerase [20].
The histogram representing the distance of the active polymerases to the EC/HC interface shows that 66% of the active enzyme peaks at 20+/−20 nm from the interface.
It is responsible for tethering active polymerases to DNA during replication and serves as a starting point for our modelling approach.
One idea put forward to explain chromatin loops is the existence of transcription factories or active chromatin hubs, where active polymerases cluster and thereby co-locate genes and regulatory elements [23], [24].
Since this nascent transcription reflects the amount of active polymerases on the tested template, the results indicate that RNase P determines the transcription output by Pol I and Pol III.
Nuclear run-on transcription assays indicate that the rate of nascent transcription of rDNA and 5S rRNA genes, which reflects the number of active Pol I and Pol III on these genes, is reduced in cells with inactivated RNase P. Thus, RNase P determines the output of transcription by active polymerases.
