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In total, they're adding about 1.5 million new users every month and their most active locale is Hong Kong.
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These include residues that define the pterin-binding pocket and others within the two flexible loops DLp1 and DLp2 that are proposed to close over the active site locale [11].
For instance, a conserved arginine that is present in many members of the PDI family has been reported to modulate the pKa of the active-site cysteine residues by moving into and out of the active-site locale [ 73].
Most of the exhibits will be below ground -- long walkways through basaltic columns, dial-a-blast consoles that will show digital simulations of Mt.-St.-Helens-style explosive eruptions, and auditoriums presenting real-time data on discoveries on other active volcanic locales, even ones on Mars or the moons of Jupiter.
Though every locale with an active tourist population has hot air balloon tours, few - if any - can match up to the grandeur of Park City.
Utilizing a small number of probes designed as substrate analogs, we were able to expose a limitation in accepted substrate linkages (secondary and tertiary amides) and a flexible catalytic reduction site (C1 vs C3 reduction in diketone thioether substrates), indicating a stringent preference in linkage region with a flexible reduction locale in the active site, respectively.
These observations may be useful in distinguishing biologically active processes operating at distant locales in the Solar System where C2H2 is present.
This is probably because many mountains in Japan are of volcanic origin, while in Russia folded mountains and active volcanoes are usually in different locales.
From Maryland to Maine, similar frostbite programs keep hard-core racers happy and active during the inactive months in nippy locales.
(In many locales, spring is the most active time, but that doesn't hold true everywhere).
Locale is a dynamic settings manager.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com