Sentence examples for active internalization from inspiring English sources

We wanted to ensure that the luciferase activity present in the cytosol of KG-1 cells was dependent on active internalization.

In vitro cellular uptake in EGFR-overexpressing cell line (A549) demonstrated an active internalization of GE11-functionalized nanoparticles.

Uptake studies in HEp-2 cells indicate active internalization of InvA497-functionalized liposomes via β1-integrin receptor-mediated uptake mechanism mimicking the natural invasion strategy of Y. pseudotuberculosis.

Efficient and active internalization of mesoporous silica particles of different sizes was observed by transmission electron microscopic and flow cytometric analysis and studies using pharmacological inhibitors suggested that uptake occurred through a process of endocytosis.

Adenovirus relies on PI3K-mediated organization of actin filament for active internalization.

HB-19 is internalized at 37°C but at 20°C it remains attached to the cell surface without entering the cytoplasm, thus indicating that it uses an active internalization process.

Recent experimental results suggest that, contrary to previous assumptions, GPCRs remain active after internalization, continuing to stimulate cAMP production in association with internalized AC [44], [45].

Taken together, these results show active IgG internalization by podocytes.

Active cellular internalization is largely dependent on the inorganic core composition of the particles, size, organic shell used for glycan conjugation, and the type of glycan and cell environment (culture conditions).

It was proposed that the adaptor protein CrkII associates with Abl during infection, as evidenced by the presence of CrkII at the site of active Salmonella internalization where it colocalized with F-actin.

10, 11 On the basis of these findings, we designed a ligand-directed agent, bone metastasis-targeting peptidomimetic-11 (BMTP-11), which consists of the CGRRAGGSC motif synthesized in tandem to D KLAKLAK 2, an apoptosis-inducing motif that is active on cell internalization and has been validated in preclinical models of cancer, obesity, and retinopathies.