The well-known ferritin receptor, als3, was also identified but was found to be much more active in the damage stage than the adhesion stage.
Finally, the ubiquitin proteasome pathway is more active in the larval stage compared with the pupal stage, reminiscent of the caste-specific expression of ubiquitin-related genes in larvae of the honey bee (Chen et al. 2012; Barchuk et al. 2007; Humann and Hartfelder 2011).
Hybridization with adult worm RNA pointed to a set of genes transcriptionally active in this stage of the parasite's life cycle.
For example, if one gene cluster has high strength in a particular stage, we believe that this gene cluster is active in this stage; otherwise, the function of this gene cluster may be depressed.
In the second stage, compounds not detected as active in the first stage are evaluated by comparing the distribution of measured responses to the detection limit of the assay.
Compounds not detected as "active" in the first stage are tested for activity at the lowest tested concentration in the second stage.
In our network, hmx1 was identified as being most active in the invasion stage, indicating that hemoglobin degradation occurs mainly during the invasion stage.
However, the Dlx1 expression pattern showed heterochrony in the epithelial compartment as transcription started during the LM stage in scale buds, while it was already active in the EM stage in tooth buds.
The fact that ftr2 is active in the damage stage may be due to the higher level of iron availability [ 45].
And for Australia to make a difference in the world, you've got to be active in the world stage," Mr. Rudd told CNN this month, shortly after co-hosting a round-table discussion on climate change in Singapore that was attended by President Barack Obama and President Hu Jintao of China.
