The phrase "active in the pathogenesis of" is correct and usable in written English.
It can be used in scientific or medical contexts to describe the role of a factor or agent in the development of a disease or condition.
Example: "The researchers found that the protein was active in the pathogenesis of Alzheimer's disease."
Alternatives: "involved in the development of" or "contributing to the onset of".
And these inflammatory cytokines are active in the pathogenesis of various chronic inflammatory diseases such as multiple sclerosis, Parkinson's disease, Alzheimer's disease and colon cancer [64].
Apelinergic system may be supposed to be active in the pathogenesis of bone mineral metabolism disorders in uremic patients.
Renal toxicity and immunological disorders of the kidney result in an elevated formation of ROS which is active in the pathogenesis of kidney disease.
If miRNAs are indeed active in the pathogenesis of diabetes and its related complications, the restoration of normal function by modifying the expression of specific miRNAs may be a therapeutic target for managing this disease.
Nuclear factor kappa B (NF-κB) is a family of structurally related eukaryotic transcription factors that are persistently active in the pathogenesis of numerous malignancies, including prostate [ 2], breast [ 3, 4], colorectal [ 5], pancreatic [ 6], oral [ 7], and gastric carcinoma cancer [ 8].
However, it is known, that hepatic A2R play an active role in the pathogenesis of hepatic fibrosis [23].
Because OX40 is expressed on both CD4+ and CD8+ T cells and both subsets are known to play an active role in the pathogenesis of ECM, we next wanted to examine the distribution of OX40 among T cell subsets.
Oxidative species are not dormant products of inflammation, but active molecules in the pathogenesis of inflammatory processes.
Evidence suggesting that TNF-α plays an active role in the pathogenesis of type 1 diabetes is derived from in vitro studies and animal models.
Insights from laboratory models of acute lung injury (ALI) have suggested that hypercapnia may play an active role in the pathogenesis of inflammation and tissue injury.
Advances in our understanding of the biology of hypercapnia have prompted consideration of the potential for hypercapnia to play an active role in the pathogenesis of inflammation and tissue injury.
