Sentence examples for active in approximately from inspiring English sources

Mutated BRAFV600E is constitutively active in approximately 50% of human melanomas, causing their uncontrolled proliferation [ 29].

Ltbp1L is active in approximately 65% of luminal cells but silent within the inner body cells of the TEB, which are thought to be a proliferative progenitor population.

Telomerase is active in approximately 90% of clinical primary tumors, whereas normal human somatic cells show negligible telomerase activity in most cases.

This is highly significant as oncogenic RAS (active in approximately 30% of all human cancers) signals partly via MEK/ERK (Schubbert et al, 2007), thus further investigation of NFAT signalling in the context of oncogenic Ras/RAF is merited.

However, the MMTV promoter is only active in approximately 70% of the mammary epithelium, resulting in stochastic Cre recombinase expression in PyV mT tumour tissue; a selection for PyV mT-positive/Cre recombinase-negative cells arises in the developing tumour, precluding excision of the conditional allele of interest.

The majority of the inhibitors are in clinical trials, unlike the suberoylanilide hydroxamic acid, a pan-HDACi, and Romidepsin (FK 228), a class I-selective HDACi, which are only approved in the second line treatment of refractory, persistent or relapsed cutaneous T-cell lymphoma, and active in approximately 150 clinical trials, in monotherapy or in association.

Neuraminidase is not a target that is particularly challenging for most docking programs, as illustrated by the fact that both Glide/Gscore and Gold/Affinity are able to rank over 90% of the actives in approximately the first 10% of the database.

Mycobacterium tuberculosis infection leads to pulmonary active disease in approximately 5 10% of exposed individuals.

Ultrasound examination indicated on-going active disease in approximately one-third of children.

In vitro antigen-stimulated IFN-γ production shows a specular image, being negative in all patients during active disease, positive in approximately 50% of patients by 30 days post-treatment and detectable in almost all of them by 120 days.

19 Dividing the amount of CO formed during the electrolysis experiment over 60 min by the estimated number of active Re sites results in approximately 1400 turnovers per active site and a frequency of approximately 0.4 turnovers per second.