Sentence examples for active gist from inspiring English sources

Insufficient FDG uptake could have been the reason for the negative baseline PET in patient 21 with clinically active GIST.

Many investigational agents are potent KIT and PDGFRA inhibitors, and therefore potentially active against GIST.

As MegaFasL appeared to be an active agent in GIST cells, we studied the expression of Fas and FasL in 45 GIST samples by immunohistochemistry using a TMA.

Sunitinib administration at 37.5 mg on a continuous daily dosing (CDD) schedule has also been found to be active and feasible in RCC, GIST, and pancreatic neuroendocrine tumor [ 14- 17], and was used subsequently in sunitinib trials in MBC.

We conclude that vatalanib is active in patients who have imatinib-resistant GIST or imatinib and sunitinib-resistant GIST.

Current recommendations include 1 year adjuvant treatment in GIST patients at risk but active studies explore different durations of treatment with an interval of up to 5 years.

Current recommendations include 1 year adjuvant treatment in GIST patients at risk, but active studies explore different durations of treatment with an interval of up to 5 years duration.

Although the tyrosine kinase inhibitor imatinib has been shown to be an active agent in patients with gastrointestinal stromal tumours (GIST), complete remissions are almost never seen and most patients finally experience disease progression during their course of treatment.

A smaller subset of GISTs express wild-type Kit but constitutively active PDGFRa [17].

Vatalanib is active despite its narrow kinome interaction spectrum in patients diagnosed with imatinib-resistant GIST or with imatinib and sunitinib-resistant GIST.

This OS would undoubtedly be increased further if followed by a proven active treatment arm, such as sunitinib, which was not used for GIST at the time this phase I study was carried out.