Sentence examples similar to active gdp from inspiring English sources

As a positive control, before pull-down an aliquot of total protein lysate was pre-loaded with nonhydrolyzable GTP γS to active (GDP-bound) Ras to the GTP-bound state.

Rabs can cycle between the active GTP-bound and the non-active GDP-bound forms, assisted by different Rab-associated proteins, such as the GEFs (guanine nucleotide-exchange factors) and GAPs (GTPase-activating proteins), respectively [ 24, 26].

Like nearly all GTPases, ARF6 functions as a molecular switch alternating between GTP-bound (active) and GDP bound (inactive) states.

The guanine nucleotide exchange factors (GEF) small GTPase regulatory genes contribute to RAS activation by active removal of GDP that is then replaced by GTP with consequent immediate response in the downstream signal transduction.

The Rho family GTPases are thought to act as morphological switches by cycling between a GTP-bound (active) and GDP-bound (inactive) state to control cell morphology and motility.

RAS proteins are found as GTP-bound active and GDP-bound inactive forms.

GTPases act as molecular switches cycling between GTP-bound (active) and GDP-bound (inactive) conformations.

The Rho GTPases act as molecular switches cycling between GTP-bound (active) and GDP-bound (inactive) conformations.

Also like p47phox, Rac1 can exist in two interconvertible forms: GTP-bound (active) and GDP-bound (inactive).

The KRAS proto-oncogene encodes an ∼21 kDa small GTPase, which cycles between GTP-bound active and GDP-bound inactive states.

Rab7 GTPase function is biochemically well defined and GTP-locked 'constitutively active' and GDP-locked 'dominant negative' mutants have been tested and utilized in a plethora of systems, including human cell lines and Drosophila (Mukhopadhyay et al., 1997a, 1997b; Bucci et al., 2000; Zhang et al., 2007).