We selected CWSs located in California's San Joaquin Valley that were actively operating between 2005 and 2007, had at least one source with a geographic coordinate that could be used to estimate customer demographics, and had at least one active point-of-entry source with an arsenic sample reported during this period.
Examination of endocytosis shows that the multiple pockets are active and can facilitate entry of antibodies and lectins.
A pore in the protein complex beneath the active center may allow entry of substrates for polymerization and exit of the transcript during proofreading and passage through pause sites in the DNA.
The combination of hinge opening and rotation of Phe31 into the χ1 = 180° rotamer in the hE NADPH holoenzyme opens the active site to facilitate entry of the substrate.
In the holoenzyme (the binary complex of hDHFR with reduced nicotinamide adenine dinucleotide phosphate), a combination of hinge opening and a change in the Phe31 χ1 rotamer opens the active site to facilitate entry of the substrate.
Lysosomal ceramide generated by ASM induced the release of CTSB into the cytosol and the degradation of XIAP, resulting in the nuclear entry of active caspase-3 and subsequent apoptosis.
The complex of compound- 7 with urease is stabilized mainly through chelation of phenyl ring which is symmetrically placed between positively charged Ni ions in the active site and hindered the entry of substrate.
Consistent with this finding, it has been reported that an N-terminal His6 tag can promote PA-dependent entry of an active domain of the C2 toxin and epidermal cell differentiation inhibitor of Staphylococcus aureus.
Cholesterol binding to Scap prevents the protease-mediated release and nuclear entry of the active fragment of SREBPs, thereby blocking cholesterol synthesis and uptake from LDL (Horton et al., 2002).
