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Bias through systematic inclusion of correlated transmission networks is unlikely, as active enrolment of related partners was never in place during our entire study period.
The strengths of this study include the design with prospectively set inclusion criteria and active enrolment of a large cohort of customers and traders at markets, i.e., places where many people in the urban areas gather and work, as other sectors of employment and sites for purchasing of everyday goods are not very developed in this part of the world.
Informed consent was either obtained verbally by telephone or in writing by e-mail by the active enrolment of the GP's for an interview.
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Amongst C d there were some cases which had been missed by the active enrolment and hence no chest X-ray was available to determine whether they attributed to the total incidence of CAP.
Vital statistics: Glyndwr have a total of around 8,800 active enrolments, with over 3,000 international students.
Of the women reporting not being sexually active at enrolment, 45% (37 of 83) had not planned their most recent pregnancy, significantly more than in the sexually active group (16%, 45 of 277) (χ = 29.1, P < 0.01).
This recruitment procedure will probably have favoured enrolment of a healthier and more active group of long-term care residents.
The enrolment of this study was relatively easy with active participation by 19 of the 20 selected centres.
More active and targeted outreach is required for promoting establishment of CBE in remote localities and enrolment of the hardest to reach children.
This resulted in the enrolment of only 17 farmers.
The enrolment of patients in well-designed prospective trials is the best option at failure.
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