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The gene expression differences represent transcriptional differences at the time of specimen collection, while the differentially expressed peptides/proteins represent readily available stored protein of high abundance rather than active differences in transcription.
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Let's use an aerospace anecdote to illustrate how one-degree shifts can make an active difference to a specific course.
This and other active site differences in ValA are mostly localized to areas where the ValA substrate differs from that of DHQS.
However, the active site differences in the two structures are considerable both in terms of the loop conformation of the residues (Gly216 to Gly226) as well as the sequence of the active site residues.
These may represent acute versus chronic and latent versus active MTrP differences, respectively.
Next is a discussion of how these active site differences affect general aspects of catalysis.
This is an important family of proteins and the studies provide important insights into active site differences that could have potential impacts on function.
Therefore, to design highly selective CAIs requires the exploitation of subtle active site differences; predominantly residues found in the hydrophilic and hydrophobic pockets [ 22].
However, no review has focused on combining the obtained results from different studies on different active ingredients with differences in experimental designs, analysts and analysis equipment.
The first part of (21) describes the active power difference between the two systems and this difference is approximately 0 when the converter power loss is neglected.
The retrieved control cohort was slightly older (mean difference, 5 years; p = 0.01) and slightly more active (median difference, 1; p = 0.048; Table 1).
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